Which gastric cancer type is described as gland-forming and cohesive cells?

Prepare for the CVP and GI Pathology Exam 2 with detailed questions and comprehensive explanations. Enhance your understanding of key topics to increase your chances of passing with confidence and excel in your exams!

Multiple Choice

Which gastric cancer type is described as gland-forming and cohesive cells?

Explanation:
Gastric cancer categorized as intestinal type forms gland-like structures with cohesive cells, resembling intestinal epithelium. This glandular architecture reflects organized, connected cells that line tubules, giving rise to recognizable glands in the tumor. The intestinal type is often linked to chronic gastritis and intestinal metaplasia and tends to grow as these glandular formations. In contrast, the other patterns don’t fit this description. Diffuse type shows discohesive cells, including signet-ring cells, that invade as individual cells without forming glands, often leading to thickening and stiffening of the stomach wall (linitis plastica). Papillary-type lesions feature papillary fronds rather than true glandular glands. Therefore, the gland-forming and cohesive-cell pattern points to the intestinal type.

Gastric cancer categorized as intestinal type forms gland-like structures with cohesive cells, resembling intestinal epithelium. This glandular architecture reflects organized, connected cells that line tubules, giving rise to recognizable glands in the tumor. The intestinal type is often linked to chronic gastritis and intestinal metaplasia and tends to grow as these glandular formations.

In contrast, the other patterns don’t fit this description. Diffuse type shows discohesive cells, including signet-ring cells, that invade as individual cells without forming glands, often leading to thickening and stiffening of the stomach wall (linitis plastica). Papillary-type lesions feature papillary fronds rather than true glandular glands. Therefore, the gland-forming and cohesive-cell pattern points to the intestinal type.

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